Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4608)
Related Products (4608)
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Anticancer agent 346
0 ImagesCat. No.: HY-184941CAS No.: 3099596-05-8Anticancer agent 346 is an anticancer agent. Anticancer agent 346 exhibits anticancer activity against breast cancer.
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Acetylpyrazine (Standard)
0 ImagesCat. No.: HY-W007692RCAS No.: 22047-25-2Synonyms: 2-Acetylpyrazine (Standard)Acetylpyrazine (2-Acetylpyrazine) (Standard) is the analytical standard of Acetylpyrazine. This product is intended for research and analytical applications. Acetylpyrazine is a ketone compound and can be used for drug synthesis.
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Lipoxin B4 methyl ester
0 ImagesCat. No.: HY-134123CAS No.: 97589-07-6Synonyms: LXB4 methyl esterLipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 (LTB4; Item No. 20110) and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.
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Bimatoprost isopropyl ester
0 ImagesCat. No.: HY-116161CAS No.: 130273-87-915(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
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D-Lyxose-d
0 ImagesCat. No.: HY-128753S6CAS No.: 288846-88-8D-Lyxose-d is the deuterium labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose.
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TRPM8 antagonist 4 prodrug
0 ImagesCat. No.: HY-174846TRPM8 antagonist 4 prodrug (Compound 8b) is an orally active CB2R agonist (EC50: 51.2 nM) and a weak TRPM8 antagonist. TRPM8 antagonist 4 prodrug is a prodrug of TRPM8 antagonist 4 (HY-174825). TRPM8 antagonist 4 prodrug exhibits anti-inflammatory and analgesic activities and can be used in the research of inflammation-related pain disorders.
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4-Fluorobenzoic acid-13C6
0 ImagesCat. No.: HY-W013677S4-Fluorobenzoic acid-13C6 is the 13C6 labeled 4-Fluorobenzoic acid (HY-W013677). 4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity.
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L-Xylose (Standard)
0 ImagesL-Xylose (Standard) (L-(-)-Xylose (Standard)) is the analytical standard of L-Xylose (HY-78139). This product is intended for research and analytical applications. L-Xylose (L-(-)-Xylose) is a rare sugar and the levorotatory form of Xylose (HY-N0537). L-Xylose can be used as a raw material for the synthesis of various drugs and bioactive molecules.
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Acamelin
0 ImagesCat. No.: HY-119958CAS No.: 74161-27-6Acamelin is a Benzofuranoquinone compound that acts as a contact sensitizer. It can be isolated from the heartwood of Acacia melanoxylon R. Br., an Australian blackwood. Acamelin induces positive skin reactions and contact allergy in guinea pigs. It is applicable to research related to allergic contact dermatitis.
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L-Proline 4-methoxy-β-naphthylamide hydrochloride
0 ImagesCat. No.: HY-131096CAS No.: 100930-07-2Synonyms: H-Pro-4MβNA hydrochlorideL-Proline 4-methoxy-β-naphthylamide hydrochloride (H-Pro-4MβNA hydrochloride) can be used for Fap-activated anti-tumor compounds preparaction.
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2-Acetylpyrrole (Standard)
0 Images2-Acetylpyrrole (Standard) is the analytical standard of 2-Acetylpyrrole (HY-W012956). This product is intended for research and analytical applications. 2-Acetylpyrrole is an organic compound containing a pyrrole ring. 2-Acetylpyrrole is one of the products of the Maillard browning reaction and can serve as a major flavor component in many foods. As an intermediate, 2-acetylpyrrole can also be used in the synthesis of other active compounds, such as the flavor compound 2-acetyl-1-pyrroline.
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Gemcadiol
0 ImagesCat. No.: HY-121583CAS No.: 35449-36-6Gemcadiol is a potent antilipemic agent. Gemcadiol has the potential for the research of hyperlipoproteinemia.
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Bimatoprost methyl ester
0 ImagesCat. No.: HY-B0191BCAS No.: 38315-47-8
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N3-VC-PAB-PNP
0 ImagesCat. No.: HY-153486CAS No.: 2285374-43-6N3‑VC‑PAB‑PNP is a click chemistry intermediate containing an azide group. N3-VC-PAB-PNP serves as a linker for Bicycle STING conjugates (BSCs). N3‑VC‑PAB‑PNP is applicable in immunity and cancer-related research.
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Secoisolariciresinol (Standard)
0 ImagesCat. No.: HY-N6071RCAS No.: 29388-59-8Synonyms: (-)-Secoisolariciresinol (Standard)Artemether (Standard) ((-)-Secoisolariciresinol (Standard)) is the analytical standard of Artemether (HY-N6071). This product is intended for research and analytical applications. Secoisolariciresinol ((-)-Secoisolariciresinol) is a plant lignan and a precursor of enterolignans. Secoisolariciresinol can be converted into enterodiol and enterolactone by intestinal microflora. Secoisolariciresinol may reduce the risk of cancer and cardiovascular diseases.
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JNJ-27548547
0 ImagesCat. No.: HY-185585CAS No.: 303983-00-8JNJ-27548547, Mitomycin C (HY-13316) prodrug, is a Mitomycin C and lipophilic group conjugate. JNJ-27548547 undergoes thiolytic cleavage of its dithiobenzyl linker in the presence of reducing agents to release active substance Mitomycin C. JNJ-27548547 is formulated into pegylated liposomes (PL-MLP) with high antitumor activity in mice models.
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1-Methylpyrrolidine-d8
0 ImagesCat. No.: HY-128383SCAS No.: 131857-29-91-Methylpyrrolidine-d8 is the deuterium labeled 1-Methylpyrrolidine (HY-128383). 1-Methylpyrrolidine is a methylated pyrrolidine, and cation with thermal-origin negative nonlinear optical (self-defocusing) properties.
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2-(4-Bromophenoxy)ethanol
0 ImagesCat. No.: HY-44408CAS No.: 34743-88-92-(4-Bromophenoxy)ethanol is a Benzene compound and an intermediate.
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L-Ribose (Standard)
0 ImagesCat. No.: HY-W008351RCAS No.: 24259-59-4L-Ribose (Standard) is the analytical standard of L-Ribose (HY-W008351). This product is intended for research and analytical applications. L-Ribose is the enantiomer of D-ribose (HY-113375). L-Ribose replaces D-ribose to synthesize L-ribonucleic acid in cells, leading to erroneous gene transcription. L-Ribose serves as a starting material for L-nucleoside analogs, glycoconjugates and oligonucleotides. L-Ribose can be used in research related to hepatitis B virus infection, hepatitis C virus infection, hepatitis D virus infection, Epstein-Barr virus infection and cytomegalovirus infection.
